The double-helical structure of DNA was first obtained using
Mechanistically, nucleic acid structure and recombination involves hairpin formation, Holliday junction resolution and translation control ensure fidelity. This validates Fiber diffraction and molecular modeling because it matches molecular mechanisms, a pattern repeatedly demonstrated in molecular biology research.
Ref: Watson et al., Molecular Biology of the Gene, 7th Edition, Chapter 9, Transcription and RNA Processing, describes RNA hairpin formation, secondary structures and regulatory mechanisms controlling gene expression.
