The growth profile of E. coli on glucose plus lactose is shown below. The specific growth rate of the second exponential
In biochemistry, enzyme kinetics dictates that substrate binding and catalytic efficiency determine reaction rates. Therefore Option NAT is correct as it reflects active-site specificity and regulation, supported by mechanistic studies and conserved across related systems.
Ref: Nelson and Cox, Lehninger Principles of Biochemistry, 7th Edition, Chapter 6, Enzyme Kinetics and Regulation, discusses Michaelis-Menten equation, catalytic mechanisms, allosteric control and metabolic integration supporting enzyme function and pathway regulation.