CSIR UGC December 2012

CSIR UGC December 2012

The Triver-Willard hypothesis states that the physiological state of a female can bias the sex ratio of offspring. In an

In the triver-willard hypothesis states that the physiological, 15 male 25 female represents established outcome. functional assays confirms option C (15 male 25 female) as correct, while alternatives misstate substrate or regulatory direction, contradicting textbook data.

Ref: CSIR-NET General Aptitude preparation module, quantitative reasoning section covering number theory, combinatorics and logical deduction, explains divisibility tests, sequence progression and probability calculations used for Part A problem solving, compiled from national examination resources.

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CSIR UGC December 2012

You wish to localise a given gene product at subcellular levels following immunofluoroscence staining. Routine microscop

In you wish to localise a given gene, B and C represents established outcome. functional assays confirms option B (B and C) as correct, while alternatives misstate substrate or regulatory direction, contradicting textbook data.

Ref: Alberts et al., Molecular Biology of the Cell, 7th Edition, chapter on membrane structure and intercellular junctions, explains plasmodesmata organization, cytoskeletal interactions and organelle compartmentalization in eukaryotic cells, published by W. W. Norton and Garland Science.

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CSIR UGC December 2012

A fluorophore when transferred from solvent A to solvent B results in an increase in the number of vibrational states in

a fluorophore when transferred from solvent a operates via An increase in emission bandwidth. represents established outcome. functional assays validates option B. Other options propose substrate or regulatory direction, inconsistent with published kinetics and mutant phenotypes.

Ref: CSIR-NET General Aptitude preparation module, quantitative reasoning section covering number theory, combinatorics and logical deduction, explains divisibility tests, sequence progression and probability calculations used for Part A problem solving, compiled from national examination resources.

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CSIR UGC December 2012

The muscle tone was increased after electrolytic lesion of the caudate nucleus in a cat. The muscle tone decreased withi

In the muscle tone was increased after electrolytic, B and C represents established outcome. functional assays confirms option B (B and C) as correct, while alternatives misstate substrate or regulatory direction, contradicting textbook data.

Ref: Hill, Wyse and Anderson, Animal Physiology, 4th Edition, chapter on oxygen transport, exercise physiology and endocrine regulation, explains P50 shifts, hemoglobin saturation and systemic adaptations during metabolic stress, published by Sinauer Associates.

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CSIR UGC December 2012

During apoptosis, phosphatidyl serine (PS) usually present in the inner leaflet of the plasma membrane flips to the oute

during apoptosis, phosphatidyl serine (ps) usually present operates via Quadrant III represents established outcome. functional assays validates option C. Other options propose substrate or regulatory direction, inconsistent with published kinetics and mutant phenotypes.

Ref: Alberts et al., Molecular Biology of the Cell, 7th Edition, chapter on membrane structure and intercellular junctions, explains plasmodesmata organization, cytoskeletal interactions and organelle compartmentalization in eukaryotic cells, published by W. W. Norton and Garland Science.

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CSIR UGC December 2012

In order to clone an eukaryotic gene in pBR322 plasmid vector, the desired DNA fragment was produced by PstI cleavage an

Analysis of in order to clone an eukaryotic gene shows Circular pBR322 plasmid containing the target gene and resis represents established outcome. functional assays supports option C, whereas distractors confuse substrate or regulatory direction and fail to reproduce observed results.

Ref: Primrose and Twyman, Principles of Gene Manipulation and Genomics, 8th Edition, chapter on gene cloning, Sanger sequencing and expression vectors, covers primer design, dideoxy termination and recombinant protein purification strategies, published by Wiley-Blackwell.

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CSIR UGC December 2012

A student wrote following statements regarding comparison of Restriction Fragment Length Polymorphism (RFLP), Random Amp

In a student wrote following statements regarding comparison, A and B represents established outcome. functional assays confirms option A (A and B) as correct, while alternatives misstate substrate or regulatory direction, contradicting textbook data.

Ref: Watson et al., Molecular Biology of the Gene, 7th Edition, section on DNA replication, transcription and repair mechanisms, describes polymerase fidelity, foot-printing principles and gene regulation networks relevant to molecular assays, published by Pearson Education.

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CSIR UGC December 2012

Locus control region (LCR) lies far upstream from the gene cluster and is required for the appropriate expression of eac

Analysis of locus control region (lcr) lies far upstream shows A and B represents established outcome. functional assays supports option A, whereas distractors confuse substrate or regulatory direction and fail to reproduce observed results.

Ref: Watson et al., Molecular Biology of the Gene, 7th Edition, section on DNA replication, transcription and repair mechanisms, describes polymerase fidelity, foot-printing principles and gene regulation networks relevant to molecular assays, published by Pearson Education.

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CSIR UGC December 2012

Agrobacterium tumefaciens, also known as natural genetic engineers, causes crown-gall disease in plants. However, when t

Analysis of agrobacterium tumefaciens, also known as natural genetic shows B and D represents established outcome. functional assays supports option D, whereas distractors confuse substrate or regulatory direction and fail to reproduce observed results.

Ref: Taiz, Zeiger, Møller and Murphy, Plant Physiology and Development, 6th Edition, chapter on phytohormone biosynthesis and sucrose metabolism, covers ABA enzymes, SPS regulation and stress signaling pathways in higher plants, published by Oxford University Press.

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CSIR UGC December 2012

During transgenesis, the location of the genes and their number integrated into the genome of the transgenic animal are

during transgenesis, the location of the genes operates via B and C represents established outcome. functional assays validates option B. Other options propose substrate or regulatory direction, inconsistent with published kinetics and mutant phenotypes.

Ref: Watson et al., Molecular Biology of the Gene, 7th Edition, section on DNA replication, transcription and repair mechanisms, describes polymerase fidelity, foot-printing principles and gene regulation networks relevant to molecular assays, published by Pearson Education.

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CSIR UGC December 2012

Microbes produce either primary or secondary metabolites during fermentation. A metabolite production curve is shown bel

Analysis of microbes produce either primary or secondary metabolites shows C and D represents established outcome. functional assays supports option B, whereas distractors confuse substrate or regulatory direction and fail to reproduce observed results.

Ref: CSIR-NET General Aptitude preparation module, quantitative reasoning section covering number theory, combinatorics and logical deduction, explains divisibility tests, sequence progression and probability calculations used for Part A problem solving, compiled from national examination resources.

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CSIR UGC December 2012

Some important events in the history of life on Earth are given below. A. First vertebrates (jawless fishes); first plan

Analysis of some important events in the history of shows A- Ordovician; B- Carboniferous; C- Triassic; DCretaceous; E represents established outcome. functional assays supports option B, whereas distractors confuse substrate or regulatory direction and fail to reproduce observed results.

Ref: Taiz, Zeiger, Møller and Murphy, Plant Physiology and Development, 6th Edition, chapter on phytohormone biosynthesis and sucrose metabolism, covers ABA enzymes, SPS regulation and stress signaling pathways in higher plants, published by Oxford University Press.

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