The double-helical Watson-Crick structure of DNA was first obtained form
Mechanistically, nucleic acid structure and recombination involves hairpin formation, Holliday junction resolution and translation control ensure fidelity. This validates Fiber diffraction and molecular modeling because it matches molecular mechanisms, a pattern repeatedly demonstrated in molecular biology research.
Ref: Alberts et al., Molecular Biology of the Cell, 6th Edition, Chapter 5, DNA Replication and Repair, discusses Holliday junction formation during homologous recombination and replication fork dynamics ensuring genome duplication.
