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#tensile strength

2 public questions tagged with this topic.

Cytoskeleton

Which of the following cytoskeletal elements provides tensile strength to cells?

Cytoskeletal polymers provide complementary mechanical functions. F actin, 7 nanometer double helical polymer of ATP loaded G actin, drives protrusion and contraction via myosin II and generates branched networks via Arp2/3 at 70 degrees. Microtubules, 25 nanometer hollow cylinders of alpha beta tubulin heterodimers with GTP cap, resist compression and act as long range highways for kinesin plus end and dynein minus end motors transporting organelles and chromosomes. Intermediate filaments, 10 nanometer non polar fibers, provide outstanding tensile strength and resilience. Assembly hierarchy i

Ref: Alberts et al., Molecular Biology of the Cell, 7th ed., Chapter 16: Cytoskeleton and Intermediate Filaments.

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Cell Communication and ECM

Which ECM component provides tensile strength?

Collagens, is consistent with established principles of cell signaling, receptor pharmacology and cellular regulation. Experimental measurements of binding parameters, genetic loss-of-function studies and pharmacological interventions all converge on the same interpretation. Related options address neighboring concepts but do not satisfy the precise criterion stated in the question.

Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)

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