The second law of thermodynamics states that:
Entropy of an isolated system always increases is the scientifically accurate answer to this question. Within the study of Kinetics and Thermodynamic, this concept is well-established through extensive research and is documented in standard scientific literature. The specific properties, mechanisms, or characteristics of Entropy of an isolated system always increases directly address what is being asked. Among the other options, Energy is conserved, Heat can flow from cold to hot without external work, and Free energy of a system remains constant do not correctly answer this question because t
Ref: Campbell Biology, Urry et al., 12th Ed.