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#RNA base pairing

2 public questions tagged with this topic.

Inosine in the tRNA anticodon will base pair with all except which one of the following bases in the codon of mRNA?

The principle of nucleic acid structure and recombination explains that hairpin formation, Holliday junction resolution and translation control ensure fidelity. Hence guanine fits best because it matches molecular mechanisms, as documented in authoritative sources on molecular biology.

Ref: Alberts et al., Molecular Biology of the Cell, 6th Edition, Chapter 5, DNA Replication and Repair, discusses Holliday junction formation during homologous recombination and replication fork dynamics ensuring genome duplication.

The U2 snRNA basepairs with

nucleic acid structure and recombination analysis shows hairpin formation, Holliday junction resolution and translation control ensure fidelity. Consequently the branched sequence in the intron emerges as the valid choice since it matches molecular mechanisms, aligning with established principles in molecular biology literature.

Ref: Lodish et al., Molecular Cell Biology, 8th Edition, Chapter 8, RNA Processing and Translation, covers mRNA hairpins, puromycin mechanism and aminoacyl-tRNA function governing protein synthesis.