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Phosphodiester bonds connect nucleotides in a DNA strand, linking the phosphate of one nucleotide to the sugar of another.
Ref: NCERT Class 12 Biology Chapter 5: Molecular Basis of Inheritance Human Genome Project and DNA Fingerprinting
Formation of unusual 2'-5' phosphodiester bond distinguishes Group II and spliceosomal splicing from Group I. During first transesterification, nucleophilic attack by 2' hydroxyl of branchpoint adenosine on phosphodiester at 5' splice junction creates branched RNA where intron 5' terminus connected to branch Adenosine via 2'-5' linkage, producing lariat with loop and 3' tail. Group I splicing retains standard 3'-5' linkages using external G. Detecting 2'-5' bond is diagnostic marker for lariat introns and spliceosomal catalysis in sequencing studies. This refined regulation supports accurate r
Ref: Berg et al., Biochemistry, 9th ed., Chapter 32, 2'-5' phosphodiester bond in Group II lariat splicing
Two sugars via phosphate is the scientifically accurate answer to this question. Within the study of Nucleic Acid, this concept is well-established through extensive research and is documented in standard scientific literature. The specific properties, mechanisms, or characteristics of Two sugars via phosphate directly address what is being asked. Among the other options, The base to the sugar, Two nitrogenous bases, and The sugar to the phosphate do not correctly answer this question because they either refer to different concepts, describe properties of other molecules or processes, or repre
Ref: Campbell Biology, Urry et al., 12th Ed.
The 5' carbon of one nucleotide to the 3' carbon of the next nucleotide is the scientifically accurate answer to this question. Within the study of DNA, this concept is well-established through extensive research and is documented in standard scientific literature. The specific properties, mechanisms, or characteristics of The 5' carbon of one nucleotide to the 3' carbon of the next nucleotide directly address what is being asked. Among the other options, The nitrogenous base to the sugar, Two nitrogenous bases, and The phosphate group to the nitrogenous base do not correctly answer this quest
Ref: Molecular Biology of the Gene, Watson et al., 7th Ed.
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