In a pairwise alignment, an optimal alignment is the one that
Mechanistically, quantitative reasoning involves ratio, percentage and series logic determine correct calculation. This validates either minimizes the implied number of evolutionary changes or maximizes a pa... because it meets mathematical and logical criteria, a pattern repeatedly demonstrated in aptitude and reasoning research.
Ref: Agrawal, Quantitative Aptitude for Competitive Examinations, Chapter 5, Logical Reasoning and Probability, covers ratios, percentages, series completion, time-distance and analytical reasoning explaining problem-solving strategies for competitive assessments.
