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#infectious disease

14 public questions tagged with this topic.

Which of the following statements about AIDS is correct?

AIDS is caused by HIV, which destroys CD4+ T-lls, leading to immune system failure. This follows from NCERT principle where the relation explains the outcome clearly for students in simple steps.

Ref: NCERT Biology Textbook for Class XI and XII (Zoology section), Chapter: Human Health and Disease, Topic: Immunity, diseases and health maintenance.

Which mosquito-borne disease is characterized by recurring fever and chills?

Malaria, caused by Plasmodium species, is characterized by recurring fever and chills due to the release of haemozoin toxin. This follows from latest NCERT 2026-27 principle explaining the concept clearly for NEET students in simple steps as per rationalized syllabus.

Ref: NCERT Biology Textbook - Latest Edition for Academic Session 2026-27 (Zoology section, Rationalized Textbook for Class XI and XII), Chapter: Biology - Zoology portion (Latest NCERT Textbooks for Academic Session 2026-27 - Rationalized Edition for Class XI and XII), Topic: Structural organization, physiology, human health and related concepts as per latest syllabus.

Which of the following sexually transmitted infections (STIs) is caused by a bacterial pathogen?

Gonorrhea is caused by the bacterium *Neisseria gonorrhoeae*, whereas HIV/AIDS, genital herpes, and Hepatitis B are caused by viruses. This follows from NCERT principle where the relation explains the outcome clearly for students in simple steps.

Ref: NCERT Biology Textbook for Class XI and XII (Zoology section), Chapter: Biology - Zoology portion covering relevant system and function.

Which of the following antibiotics is bactericidal?

Glycopeptide antibiotics exhibit true bactericidal killing activity rather than simple growth arrest, a distinction critical for treating severe Gram-positive infections. Vancomycin functions by recognizing and binding with high affinity to the D-alanyl-D-alanine dipeptide terminus of the peptidoglycan precursor lipid II that is exposed on the outer face of the cytoplasmic membrane after flipping from the cytoplasm. This binding creates a large steric cap that prevents transglycosylases from polymerizing the alternating N-acetylglucosamine and N-acetylmuramic acid glycan chain and simultaneously blocks transpeptidases, the penicillin-binding proteins, from forming peptide cross-links between stems. Without cross-linking, the nascent peptidoglycan mesh in Gram-positive organisms with 20-80 nm thick wall remains mechanically weak and cannot withstand internal turgor pressures of 20 atmospheres, leading to activation of autolysins and osmotic lysis. Tetracycline, erythromycin and clindamycin bind reversibly to bacterial ribosomes, pausing translation temporarily and causing bacteriostatic arrest where cells resume growth after drug removal, explaining clinical preference for vancomycin in MRSA bacteremia and endocarditis where rapid killing is desired.

Ref: Madigan et al., Brock Biology of Microorganisms, 16th ed., Chapter 5: Glycopeptide Antibiotics and Cell Wall Inhibition.

Receptor for cholera toxin is:

Cholera toxin catalyzes ADP-ribosylation of Gαs, locking the subunit in its GTP-bound active form by inhibiting GTPase activity. Persistent activation of adenylyl cyclase produces massive elevations of cAMP in intestinal epithelial cells, leading to continuous opening of chloride channels and the characteristic watery diarrhea of cholera. Careful

Ref: NCERT Biology Class 11–12 Alberts et al Molecular Biology of the Cell Lodish et al, Molecular Cell Biology Cooper & Hausman, The Cell Abbas et al., Cellular and Molecular Immunology (for immunology sections)