The common type of duplication generates a second copy of the gene
Mechanistically, metabolic engineering and inheritance involves exogenous gene introduction and pathway extension enable trait improvement. This validates in close proximity of the first copy because it demonstrates metabolic extension and combinatorial biosynthesis, a pattern repeatedly demonstrated in genetics and biotechnology research.
Ref: Pierce, Genetics: A Conceptual Approach, 6th Edition, Chapter 3, discusses genotype-phenotype correlation and inheritance patterns providing framework for genetic transmission and metabolic engineering.
