Which of the following best describes the Fluid Mosaic Model?
Proposed by S.J. Singer and G.L. Nicolson in 1972 based on freeze-fracture electron microscopy and cell fusion experiments, the Fluid Mosaic Model describes membrane as two-dimensional solution where amphipathic lipids form viscous fluid matrix, about 100-fold more viscous than water, within which integral membrane proteins float as mosaic of diverse functions including pumps, receptors, adhesion molecules, and enzymes. Phospholipids exhibit rapid lateral diffusion around 10^-8 cm2 per second, rotation around axis, flexing of chains, but slow transverse flip-flop unless catalyzed by flippases,
Ref: Alberts et al., Molecular Biology of the Cell, 7th ed., Chapter 10: Fluid Mosaic Model, Singer and Nicolson.
