First GM crop approved for human consumption was:
Flavr Savr tomato developed by Calgene Inc., Davis, California, holds historical status as first genetically modified whole food approved for commercial sale and human consumption. FDA completed voluntary consultation DST 1994 after molecular characterization, Southern blot showing two contiguous T-DNA inserts, compositional analysis comparing sugars, acids, lycopene, vitamin C, glycoalkaloids to non-transgenic parent, toxicity assessment of NPTII at acute dosing in mice, and allergenicity search revealing no homology to known allergens. USDA APHIS determined nonregulated status under 7CFR 340
Ref: Redenbaugh et al. Safety assessment Flavr Savr FDA 1992; Bruening & Lyons 2000 Food Chem Toxicol.
