In bony fishes, Immunoglobulin IgM is secreted as a
antibody structure analysis shows immunoglobulin fold with antiparallel beta-sandwich provides antigen binding. Consequently Tetramer emerges as the valid choice since it demonstrates immune recognition architecture, aligning with established principles in immunology literature.
Ref: Janeway et al., Immunobiology, 9th Edition, Chapter 3, Antigen Recognition, discusses immunoglobulin fold, beta-sandwich of antiparallel beta sheets, antibody structure and humoral immunity explaining specificity.