In a transplantation experiment, the presumptive ectoderm from an early frog gastrula was placed in a newt gastrula’s mo
Classic Spemann and Mangold style cross-species grafts test specificity of induction and origin of pattern information. Presumptive ectoderm from early frog gastrula transplanted into newt gastrula mouth region still forms frog-specific keratinized mouth structures with characteristic papillae, cement gland histology and mucus composition, rather than newt-type morphology. Inductive signal from underlying pharyngeal endoderm and cranial neural crest triggers mouth formation, but response genome determines species-specific shape and cytology. Regional specificity would mean location determines
Ref: Gilbert, Developmental Biology, 12th ed., Chapter 3: Genetic Specificity of Induction in Cross-Species Grafts.
