Live attenuated vaccines are contraindicated in:
Live attenuated vaccines contraindicated in immunocompromised individuals because control of limited replication depends on intact innate and adaptive immune compartments. Immunocompromise includes congenital severe combined immunodeficiency affecting T cells, chronic granulomatous disease phagocyte defect, HIV with CD4 count below 200 cells per microliter in adults or below 15 percent in children, chemotherapy causing neutropenia, high dose systemic corticosteroids more than 2 mg per kg prednisone for 2 weeks, biologic agents anti TNF monoclonal antibodies, organ transplant recipients receivi
Ref: CDC Contraindications immunocompromised live; Plotkin Immunocompromised host; Red Book AAP.
