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Expanded bed chromatography runs on the principle of

In biochemistry, enzyme catalysis and lipid structure dictates that substrate affinity, transition state stabilization and phospholipid composition govern function. Therefore Stroke’s law of sedimentation is correct as it reflects catalytic efficiency and membrane organization, supported by mechanistic studies and conserved across related systems.

Ref: Lehninger Principles of Biochemistry, Chapter 9, Lipids and Membranes, explains phospholipid components, glycerol, fatty acids, phosphate group and membrane structure providing foundation for lipid biochemistry.