11 public questions tagged with this topic.
In DNA, adenine pairs with thymine via two hydrogen bonds, following base-pairing rules.
Ref: NCERT Class 12 Chemistry > Chapter 14: Biomolecules > Topic: Nucleic Acids - Structure - Nucleotides, Sugars and Base Pairing
Adenine pairs with thymine in DNA via two hydrogen bonds, contributing to the double helix stability.
Ref: NCERT Class 12 Chemistry > Chapter 14: Biomolecules > Topic: Nucleic Acids - Structure - Nucleotides, Sugars and Base Pairing
Hydrogen bonds hold complementary base pairs (A-T, G-C) together in the DNA double helix.
Ref: NCERT Class 12 Chemistry > Chapter 14: Biomolecules > Topic: Nucleic Acids - Structure - Nucleotides, Sugars and Base Pairing
Guanine pairs with cytosine in DNA via three hydrogen bonds, enhancing stability.
Ref: NCERT Class 12 Chemistry > Chapter 14: Biomolecules > Topic: Nucleic Acids - Structure - Nucleotides, Sugars and Base Pairing
Guanine and cytosine form three hydrogen bonds in DNA, contributing to the stability of the double helix.
Ref: NCERT Class 12 Chemistry > Chapter 14: Biomolecules > Topic: Nucleic Acids - Structure - Nucleotides, Sugars and Base Pairing
In RNA, adenine pairs with uracil via two hydrogen bonds, unlike DNA where it pairs with thymine.
Ref: NCERT Class 12 Chemistry > Chapter 14: Biomolecules > Topic: Nucleic Acids - Structure - Nucleotides, Sugars and Base Pairing
Erwin Chargaff discovered that in DNA, the amount of adenine equals thymine and the amount of guanine equals cytosine.
Ref: NCERT Class 12 Biology Chapter 5: Molecular Basis of Inheritance Search for Genetic Material and RNA World
Purines and pyrimidines normally exist in keto-amino tautomers that form canonical Watson-Crick pairs G-C and A-T. Rare enol-imino tautomers relocate hydrogen bonding donors and acceptors altering pairing face. A transient tautomeric shift converts guanine to enol form presenting hydrogen bonding pattern similar to adenine, allowing stable pairing with thymine instead of cytosine. If uncorrected before next round of replication, replication past this mispair fixes G-C to A-T transition mutation. Phenomenon underlies spontaneous point mutations and explains mutagenesis by base analogs like bromouracil.
Ref: Watson JD et al., Molecular Biology of the Gene, 7th ed., Chapter 9: Rare tautomeric shifts and mispairing
3 is obtained by applying the relevant formula or quantitative relationship to the given parameters. In Nucleic Acid, numerical problem-solving requires understanding the mathematical relationships between biological variables. The calculation involves substituting the provided values into the appropriate equation and solving systematically. The other options (1, 2, and 4) result from common calculation errors such as using incorrect formulas, misidentifying variables, inverting ratios, or making arithmetic mistakes.
Ref: Campbell Biology, Urry et al., 12th Ed.
It involves three strands instead of two is the scientifically accurate answer to this question. Within the study of DNA, this concept is well-established through extensive research and is documented in standard scientific literature. The specific properties, mechanisms, or characteristics of It involves three strands instead of two directly address what is being asked. Among the other options, It does not form hydrogen bonds, It occurs only in RNA, and It is less stable than Watson-Crick pairing do not correctly answer this question because they either refer to different concepts, describe properties of other molecules or processes, or represent common misconceptions about this topic.
Ref: Molecular Biology of the Gene, Watson et al., 7th Ed.
Stacking interactions accurately identifies the binding site, binding partner, or molecular interaction described in this question. In DNA, molecular recognition and binding specificity are governed by complementary shape, charge, and hydrophobic interactions between molecules. Stacking interactions binds at the specified location due to its structural complementarity and specific non-covalent or covalent interactions. The other options (Hydrogen bonds, Covalent bonds, and Electrostatic attraction) describe binding to different sites, involve different types of molecular interactions, or represent incorrect binding partners.
Ref: Molecular Biology of the Gene, Watson et al., 7th Ed.
