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#B cell maturation

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Somatic mutation of Immunoglobulin gene accounts for

This outcome reflects metabolic engineering and inheritance, where exogenous gene introduction and pathway extension enable trait improvement. Option C captures this correctly because it demonstrates metabolic extension and combinatorial biosynthesis, consistent with textbook descriptions and experimental observations in genetics and biotechnology.

Ref: Griffiths et al., Introduction to Genetic Analysis, 11th Edition, Chapter 5, discusses metabolic pathways, recombinant DNA technology, metabolic extension and Golden Rice as pathway engineering for vitamin A production.