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#AP axis

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The patterning of the nervous system along the anterior-posterior axis in embryo is controlled by

The principle of core biological organization explains that structure-function relationships govern cellular processes. Hence Hox genes fits best because it integrates fundamental principles, as documented in authoritative sources on general biology.

Ref: Campbell et al., Biology, 11th Edition, Chapter 2, Chemical Basis of Life, discusses fundamental biological principles and molecular organization providing broad foundation for life sciences understanding.