5' UTR and 3' UTR are part of
Eukaryotic messenger RNA architecture comprises 5' 7-methylguanosine cap, 5' untranslated region, central coding region translating into protein, 3' untranslated region, and polyadenosine tail. Both UTRs derived from exonic sequences retained after splicing removal of introns, hence integral parts of mature mRNA post-processing. 5' UTR contains Kozak consensus influencing initiation, while 3' UTR harbors miRNA binding sites and AU-rich elements controlling localization and decay. Rather than DNA or protein segments, UTRs represent regulatory RNA domains modulating translation efficiency and st
Ref: Alberts Chapter 6: 5' and 3' UTR part of mature mRNA; Lodish Chapter 9 UTR regulatory functions in mRNA
