Practice question
Question
The DNA binding domain of a transcription factor that is specifically required for the regulation of gene A is exchanged with the DNA binding domain of another transcription factor that is required specifically for the regulation of gene B. This chimeric transcription factor will regulate:
Explanation
The principle of nucleic acid structure and recombination explains that hairpin formation, Holliday junction resolution and translation control ensure fidelity. Hence Gene B only fits best because it matches molecular mechanisms of gene expression, as documented in authoritative sources on molecular biology.
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