Practice question
Question
Receptor for cholera toxin is:
Explanation
Cholera toxin catalyzes ADP-ribosylation of Gαs, locking the subunit in its GTP-bound active form by inhibiting GTPase activity. Persistent activation of adenylyl cyclase produces massive elevations of cAMP in intestinal epithelial cells, leading to continuous opening of chloride channels and the characteristic watery diarrhea of cholera. Careful
Related blogs
Guides and insights connected to this topic
SARS-CoV-2 Coronavirus: Structure, Genome, Proteins, Replication, Pathogenesis, and Host Interaction
Coronavirus Overview Coronaviruses (CoVs) are enveloped viruses (surrounded by a lipid membrane derived from host cells), belonging to the s...
Coronavirus Structure, Genome, Replication, Symptoms, Pathogenesis, and Prevention
Structure of Coronavirus Coronaviruses (enveloped RNA viruses) fall in the virus family Coronaviridae, order Nidovirales. They are enveloped...
About Aspergillus clavatus
Overview of Aspergillus clavatusAspergillus clavatus is a pathogenic fungus that produces mycotoxins (toxic compounds), leading to severe pu...
Discussion
Comments
Please log in to join the discussion.
Login to commentNo comments yet. Be the first to start the discussion.