Practice question
Question
null mutation is created in a gene which is responsible for specific phosphorylation at 6th carbon position of mannose on acid hvdrolases occurring in cis-Golgi. The following statements are given towards explaining the effect of this mutation-: A. The lysosomes will be devoid of lysosomal enzymes B. Lysosomal enzymes will be secreted out C. Lysosomal enzymes will get localized in cytoplasm Which statement or combination of statements will explain the effect of mutation if the acid hydro lases :in the mutation not get degraded?
Explanation
Analysis of null mutation is created in a gene shows A and B represents established outcome. functional assays supports option D, whereas distractors confuse substrate or regulatory direction and fail to reproduce observed results.
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