Practice question
Question
A chromatin iminuno precipitation (ChIP) assay was performed to determine specific transcription factor binding sites on the promoter of a gene. Pull down was done using either IgG or anti-bodies against c-myc. A DNA containing cmyc binding regions was used as a control for PCR amplification (input). Which one of the following PCR representations of DNA is correct?
Explanation
a chromatin iminuno precipitation (chip) assay was operates via 2 represents established outcome. functional assays validates option B. Other options propose substrate or regulatory direction, inconsistent with published kinetics and mutant phenotypes.
Related blogs
Guides and insights connected to this topic
Heterochromatin - Definition, Types, Structure, Formation, Functions, Dynamics and Role in Disease
Discover heterochromatin’s dense structure, constitutive vs facultative forms, formation mechanisms, functions, and links to human disease.
Cancer Cells: Morphology, Development, Types and Differences from Normal Cells
Learn how cancer cells differ from normal cells in growth, structure, and behavior, including key morphological changes and development patterns.
SARS-CoV-2 Coronavirus: Structure, Genome, Proteins, Replication, Pathogenesis, and Host Interaction
Coronavirus Overview Coronaviruses (CoVs) are enveloped viruses (surrounded by a lipid membrane derived from host cells), belonging to the s...
Discussion
Comments
Please log in to join the discussion.
Login to commentNo comments yet. Be the first to start the discussion.