Practice question
Question
Nichrome coated stainless steel electrodes were implanted in a rat brain for chronically recording the electrical activity of deep brain structures. During a study of 3 months the intensity of electrical signals gradually decreased. The following statements may explain the cause of this observation. A. The deposition of metallic iron from the electrode tips caused degeneration of some neurons. B. The gradual accumulation of microglia at the electrode tips increased the resistance of electrodes. C. The neurons at the electrode tips were hyperpolarized gradually. D. The threshold for firing action potential in the neurons at the electrode tips was increased due to prolonged presence of electrodes. Which one of the following is correct?
Explanation
In nichrome coated stainless steel electrodes were implanted, A and B represents established outcome. functional assays confirms option B (A and B) as correct, while alternatives misstate substrate or regulatory direction, contradicting textbook data.
Discussion
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