Practice question
Question
Match the reagents in Group I with their preferred cleavage sites in Group II Group I (Agent) Group II (Cleavage Site) P) Cyanogen bromide 1) Carboxyl side of methionine Q) o -Iodosobenzoate 2) Amino side of methionine R) Hydroxylamine 3) Carboxyl side of tryptophan S) 2-Nitro-5-thiocyanobenzoate 4) Amino side of cysteine 5) Asp aragine-glycine bonds
Explanation
P-1. Q-3. R-5. S-4 is correct because it matches established general principles where p-1. q-3. r-5. s-4 represents the functional mechanism. Alternatives such as P-2. Q-3.R-1-. S-4, P-1. Q-2, R-5. S-4 contradict experimental evidence and standard textbook descriptions.
Discussion
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