Practice question
Question
HPLC is the diagnostic modality for
Explanation
High-performance liquid chromatography separates hemoglobin variants based on charge and hydrophobicity, quantifying HbA, HbF, HbS, HbA2. This makes it gold standard for diagnosing sickle cell disease, thalassemia, and other hemoglobinopathies causing hemolytic anemia.
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