Practice question

Question

The following statements are made regarding the role of cadherins in cell junctions. A. Cadherins are calcium-dependent adhesion molecules that mediate cell to cell adhesion by forming homophilic interactions. B. Cadherins function in tight junctions, sealing the space between adjacent cells. C. N-cadherins are primarily found in epithelial cells and mediate adhesion to the basal lamina. D. Cadherins are involved in the formation of focal adhesions, linking the cell cytoskeleton to the ECM. E. Cadherins interact with the actin cytoskeleton through associated proteins like catenins. Which one of the following options represents all correct statements?