Practice question

Question

Protein transport into the ER is co-translational and proteins are inserted via an aqueous channel into the ER. This can be studied using microsomes in an in vitro translation set up. Statements given below are possible outcomes when salt conductance is measured in this system. A. Microsomes do not show any conductance of salt ions when isolated from the cells. B. Addition of puromycin will lead to increased salt conductance. C. Addition of puromycin will have no effect on salt conductance. Which one of the following options has the combination of all correct statements?