Practice question
Question
N-ethylmaleimide (NEM) is known to selectively inhibit bacterial lactose transporters. Which amino acid of the transporter is responsible for this inhibition?
Explanation
The principle of enzyme catalysis and lipid structure explains that substrate affinity, transition state stabilization and phospholipid composition govern function. Hence Cysteine fits best because it reflects catalytic efficiency and membrane organization, as documented in authoritative sources on biochemistry.
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