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Question

In the Meselson and Stahl experiment, E. con was grown in a medium containing ¹⁵ NH ₄ Cl. After 24 hours, E. coli were transferred to medium containing ¹⁴ NH ₄ Cl. After the fourth generation in medium containing ¹⁴ NH ₄ Cl, the ratio between hybrids ( ¹⁵ N/ ¹⁴ N) and light ( ¹⁴ N/ ¹⁴ N) labeled DNA will be 1: n, where the value of n is

Explanation

In molecular biology, DNA replication fidelity dictates that polymerase proofreading and origin firing ensure accurate duplication. Therefore Option NAT is correct as it matches high-fidelity synthesis mechanisms, supported by mechanistic studies and conserved across related systems.

Discussion

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