Practice question
Question
In human carcinomas, many proteins including most cytoskeletal proteins undergo modifications, thereby making it difficult for a clinician to identify the origin of the cancer cells. In this context, which one of the following can be relied upon for identification of the origin of cancer cells?
Explanation
In biochemistry, enzyme catalysis and lipid structure dictates that substrate affinity, transition state stabilization and phospholipid composition govern function. Therefore Intermediate filament is correct as it reflects catalytic efficiency and membrane organization, supported by mechanistic studies and conserved across related systems.
Discussion
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