Practice question
Question
In eukaryotes, many cells can assemble a spindle in the absence of centrosomes as in the case of plant cells during mitosis, and animal cells during meiosis in females. In this context, centrosome-free mitotic extracts from frog oocytes, when supplied with beads covered with DNA, are sufficient to assemble the mitotic spindle. Listed below are a few proteins that could be involved in spindle assembly in such a setting: A. Ran GTPaseB. Ran-GEFC. TPX2D. Myosin V Which one of the following options has all proteins that are directly involved in controlling spindle assembly without centrosomes?
Explanation
In in eukaryotes, many cells can assemble a, A, B and C only represents established outcome. functional assays confirms option C (A, B and C only) as correct, while alternatives misstate substrate or regulatory direction, contradicting textbook data.
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