Practice question
Question
Excision repair systems replace a short stretch of DNA around the site of damage. The following statements are made about nucleotide excision repair In E. coli: A. UvrB homodimer creates the nicks on one strand on both side of the lesion. B. The 50-60 residue-long stretch of DNA between the two nicks Is removed by the action of UvrD. c. The gap generated is filled in typically by DNA polymerase I. D. The distortion caused by the lesion Is recognized and bound by uvrA-UvrB complex. Which one of the following options represents the combination of all correct statements?
Explanation
Analysis of excision repair systems replace a short stretch shows C and D only. represents established outcome. functional assays supports option C, whereas distractors confuse substrate or regulatory direction and fail to reproduce observed results.
Discussion
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