Practice question

Question

E. coli cultivated at 298 K uptakes an uncharged compound (A) by passive diffusion. The intracellular and extracellular concentrations of A are 0.001 M and 0.1 M, respectively. If the value of the ideal gas constant R is 1.9872 cal.mol ⁻¹ .K ⁻ ¹ , the free-energy change (in . kcalmol ⁻¹ ) for this passive diffusion of A (rounded off to two decimal places) is ___________.