Practice question

Dolly, despite originating via somatic cell nuclear transfer, possessed fully functional reproductive system with normal ovaries and estrous cycles. She mated naturally with Welsh Mountain ram named David and produced six lambs: Bonnie in 1998, followed by twins Sally and Rosie, and triplets Lucy, Darcy, and Cotton later. This demonstrated cloned animals could reproduce via conventional sexual reproduction, producing gametes through meiosis, fertilization, and embryonic development. Natural breeding success dispelled concerns cloning caused absolute sterility, though Dolly later developed premature arthritis and shortened telomeres raising questions about cloning associated epigenetic aging.