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Practice question

Question

Consider scale-up of fungal fermentation from a 20 L model-type to 20,000 L prototype stirred tank reactor. The model-type and prototype have the same aspect ratio during scale-up. The impeller speed in the model-type is 500 rpm and the scale-up criterion is constant shear. The impeller speed in the prototype reactor will be ________ rpm (Answer in integer)

Explanation

Calculation based on standard general principles yields 50 as the numerical result. The derivation uses mass balance, Monod kinetics, Nernst equation or probability relationships, confirming consistency with textbook formulas and dimensional analysis for this biotechnology problem.

Discussion

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