Practice question
Question
cAMP directly activates
Explanation
Cyclic AMP binds the regulatory subunits of protein kinase A, releasing the catalytic subunits that then phosphorylate serine and threonine residues on target proteins. This activation mechanism couples Gs-mediated stimulation of adenylyl cyclase to the phosphorylation of enzymes, ion channels and transcription factors, thereby translating the extracellular signal into diverse cellular responses.
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