Practice question
Question
A specific Mitogen Activated Protein Kinase (MAPK) cascade comprising MEKK1(a MAP3K), MKK1 (a MAP2K) and MPK6 (a MAPK) is activated sequentially in that order in Arabidopsis plants upon perceiving certain abiotic stress stimuli. The activated MPK6 phosphorylates and activates a transcription factor ‘X’, thereby making plant tolerant to the abiotic stress. Two different variants of MKK1 protein, a kinase inactive (KI) and a constitutively active (CA) forms were expressed independently in mkk1 mutant Arabidopsis plant. Considering above facts, which one of the following statements is CORRECT?
Explanation
a specific mitogen activated protein kinase (mapk) operates via ‘X’ will be activated even in the absence of stimuli in CA p represents established outcome. functional assays validates option A. Other options propose substrate or regulatory direction, inconsistent with published kinetics and mutant phenotypes.
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