Practice question

MCQ

Question

A couple came for counselling following three first-trimester miscarriages and underwent chromosomal analysis. The man was found to have pericentric inversion with the karyotype 46,XY,inv8(p12q22). Which one of the following would be a correct conclusion?

Options

Choose one · Correct answer highlighted

This is a normal variant, likely of no significance This is an abnormal chromosome that would cause congenital anomalies if transmitted to a child. This rearrangement might lead to chromosomal imbalance in an offspring and could explain multiple miscarriages. Correct This rearrangement might cause dicentric or acentric chromosomes in an offspring, which would probably not be compatible with survival

Explanation

This outcome reflects core biological organization, where structure-function relationships govern cellular processes. Option C captures this correctly because it integrates fundamental life science principles, consistent with textbook descriptions and experimental observations in general biology.

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Class IX Science 14 Sep 2026

Practice question

A couple came for counselling following three first-trimester miscarriages and underwent chromosomal analysis. The man was found to have pericentric inversion with the karyotype 46,XY,inv8(p12q22). Which one of the following would be a correct conclusion?

Options

Explanation

Comments

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