Practice question

Question

The following statements were made about X-chromosome inactivation in humans: A. Maternally-derive d X-chromosome has a greater chance of becoming inactivated in any given cell. B. Both X-chromosomes are activated during the process of oogenesis. C. The XIST gene encodes for a single, long non-coding transcript, which binds with the X-chromosome and helps in its inactivation. D. The XIST gene expression is required to initiate inactivation of X- chromosome, and also to maintain inactivation from one cell generation to the next. E. Tsix transcription affects the abundance of Xist RNA in cis. Which one of the following options represents the combination of all correct statements?