Practice question
Question
The effects of stimulation of cholinergic vagal fibers on the pacemaker potential of the cells of sinoatrial (SA) node of heart and on the nodal impulse generation are suggested below: A. The nodal cell membrane becomes depolarized. B. The slope of the pacemaker potential is increased. C. The K⁺ conductance of nodal cell membrane is decreased. D. The depolarizing effect of 'h' current (Ih) on the membrane potential is slowed down due to the opening of G protein gated K⁺channels. E. The opening of Ca⁺⁺cha1mels are slowed down due to the decreased cAMP level in the nodal cells. Which one of the following options represents the combination of all correct statements?
Explanation
In the effects of stimulation of cholinergic vagal, D and E represents established outcome. functional assays confirms option D (D and E) as correct, while alternatives misstate substrate or regulatory direction, contradicting textbook data.
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