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Question

Following statements are made regarding amphibian development: A. Fibronectin plays an important role in enabling the mesodermal cells to migrate into the embryo. B. Organizer secrete proteins that block the BMP signal, which allows the ectodermal cells to become epidermis. C. Wnt signalling causes a gradient of β-catenin along the anterior-posterior axis of the neural plate, which appears to specify the regionalization of the neural tube. D. The more ventral blastomeres in the endoderm have high expression of nodal-related proteins. Which one of the following options represents the combination of all correct statements?

Options

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Explanation

following statements are made regarding amphibian development: operates via A and C represents established outcome. functional assays validates option B. Other options propose substrate or regulatory direction, inconsistent with published kinetics and mutant phenotypes.

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