Practice question

Question

The physiological regulation of plasma osmolality by osmotically active neurons (osmoreceptors) in the organum vasculosum of lamina terminalis (OVLT) of hypothalamus is described in the following statements: A. In hyperosmolar state, the non-selective cationic channels in the osmoreceptor membrane become active causing hyperpolarization of receptor cells.B. In hyperosmolar state, shrinkage of osmoreceptor cells occurs.C. Activated osmoreceptors send action potentials to the supraoptic nucleus (SON) and paraventricular nucleus (PVN) to release arginine vasopressin (AVP).D. In hypoosmolar state, the stretching of osmoreceptor membrane causes inactivation of transient receptor vanilloid protein 4 (TRVP4) resulting in the activation of osmoreceptors. Which one of the following options represents a combination of all correct statements?