Practice question
Question
A sample of DNA is found to have the base composition (mole ratio) of A = 40, T = 22, G = 21 and C = 17. This suggests:
Explanation
According to Chargaff's rules, double-stranded DNA exhibits A=T and G=C equimolarity. The given composition shows A 40 ≠ T 22 and G 21 ≠ C 17, violating parity. Such imbalance indicates single-stranded DNA where base pairing does not constrain composition, often seen in some viral genomes.
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