Practice question
Question
T lymphocytes in a lymph node are concentrated in which of the following anatomical locations?
Explanation
Lymph node architecture segregates lymphocytes functionally. B cells populate follicles, germinal centers, and mantle zones, while T cells localize predominantly in deep cortex paracortex surrounding high endothelial venules adjacent to follicles, where dendritic cells present antigen entering via afferent lymph.
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