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Question

Which of the following amino acids is critical in the folding of proteins due to the slow isomerization of the peptide bond preceding this amino acid depending upon the solvent environment?

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Choose one · Correct answer highlighted

Explanation

The principle of enzyme catalysis and lipid structure explains that substrate affinity, transition state stabilization and phospholipid composition govern function. Hence Proline fits best because it reflects catalytic efficiency and membrane organization, as documented in authoritative sources on biochemistry.

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