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Question

The pH of gastric acid (HCl) in the human stomach lumen can be as low as 1.5. Still, normally, it does not corrode the gastric mucosa because:

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Explanation

Gastric mucosa secretes bicarbonate-rich mucus forming protective gel layer over epithelium. This barrier neutralizes acid locally, prevents back-diffusion of H+ ions and contains prostaglandins maintaining blood flow, thus protecting stomach lining from autodigestion despite pH 1.5.

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