Practice question
Question
The pH of gastric acid (HCl) in the human stomach lumen can be as low as 1.5. Still, normally, it does not corrode the gastric mucosa because:
Explanation
Gastric mucosa secretes bicarbonate-rich mucus forming protective gel layer over epithelium. This barrier neutralizes acid locally, prevents back-diffusion of H+ ions and contains prostaglandins maintaining blood flow, thus protecting stomach lining from autodigestion despite pH 1.5.
Discussion
Comments
Please log in to join the discussion.
Login to commentNo comments yet. Be the first to start the discussion.