Practice question
Question
Identify the correct order in which extra-cellular signals are transmitted. (A) Adenylate cyclase (B) cAMP (C) Protein kinase A Choose the correct answer from the options given below:
Explanation
Extracellular signals activate G-protein coupled receptors stimulating adenylate cyclase to synthesize cAMP from ATP. cAMP then activates protein kinase A, which phosphorylates downstream targets. Hence sequence is adenylate cyclase, cAMP, protein kinase A for this secondary messenger cascade.
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